Agammaglobulinemia

Agammaglobulinemia

Definition

Agammaglobulinemia is an inherited disorder in which there are very low levels of protective immune proteins called immunoglobulins. People with this disorder develop repeated infections.

Symptoms


The person may have a family history of agammaglobulinemia (or other immune disorder).

Symptoms include frequent episodes of:
  • Bronchitis
  • Chronic diarrhea
  • Conjunctivitis
  • Other respiratory infections
  • Pneumonia
  • Sinusitis
  • Skin infections
Infections typically appear in the first four years of life.

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