Graft Vs. Host Disease
Definition
Graft-versus-host disease (GVHD) is a complication that can occur after a bone marrow transplant in which the newly transplanted material attacks the transplant recipient's body.
See also: Transplant rejection
Symptoms
Symptoms in both acute and chronic GVHD range from mild to severe.
Common acute symptoms include:
* Abdominal pain or cramps
* Diarrhea
* Fever
* Jaundice
* Skin rash
* Vomiting
* Weight loss
Chronic symptoms may include:
* Dry eyes and dry mouth
* Hair loss
* Hepatitis
* Lung and digestive tract disorders
* Skin rash
In both acute and chronic GVHD, the patient is very vulnerable to infections.
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